Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458466 | 0.88 | LTB4R (0.44) | PPARALTB4RCYSLTR2CYSLTR1ACE2 | |
| SCHEMBL9717225 | 0.85 | ACE2 (0.50) | LTB4RACE2MMP2MMP9MMP12 | |
| SCHEMBL9327562 | 0.85 | MMP2 (0.45) | PPARAACE2PPARGMMP2MMP9 | |
| SCHEMBL9326086 | 0.82 | PPARA (0.43) | PPARAACE2PPARG | |
| SCHEMBL9717228 | 0.81 | NPC1 (0.51) | MMP2MMP9MMP12RARB | |
| SCHEMBL9715178 | 0.80 | RARB (0.61) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL5710099 | 0.80 | RARB (0.61) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL8769320 | 0.80 | RARB (0.61) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL8769292 | 0.80 | RARB (0.61) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10596397 | 0.80 | RARB (0.61) | PPARABIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342666-B1 | Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same | NIPPON MINING CO (JP) | 1994-03-09 | — | — | EP | disclosed |