Biphenyl

Biphenyl

SCHEMBL9327587

CCC(C)C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.53
CYP1A2 P05177 1/20 0.48
GAA P10253 1/20 0.48
CYP2C9 P11712 1/20 0.48
PKM P14618 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MME P08473 6/20 0.47
ACE P12821 6/20 0.47
APAF1 O14727 1/20 0.47
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28677008 0.88 PTGS2 (0.53) PTGS2MMEACEAPAF1
SCHEMBL9717258 0.88 SMN1; SMN2 (0.51) PTGS2MAPTSMN1; SMN2L3MBTL1HPGD
Phenol SCHEMBL27452261 0.85 LMNA (0.51) MAPTL3MBTL1APAF1
Toluene SCHEMBL27828012 0.85 LMNA (0.46) MAPTL3MBTL1APAF1
SCHEMBL27465810 0.82 CYP3A4 (0.46) MAPTL3MBTL1ACEAPAF1
SCHEMBL186666 0.81
SCHEMBL332898 0.81 GABRR1 (0.50) CYP1A2
SCHEMBL265610 0.81
SCHEMBL49960 0.81
Phenylacetic Acid SCHEMBL10921976 0.80 AKR1B1 (0.63) GAAACEHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342666-B1 Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same NIPPON MINING CO (JP) 1994-03-09 EP disclosed
US-5137653-A Alkanoyl ester compounds and their intermediates and method of producing the same NIPPON MINING CO., LTD. (JP) 1992-08-11 US disclosed
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP disclosed
US-4970023-A Biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switch elements each containing the same NIPPON MINING CO., LTD. (JP) 1990-11-13 US disclosed
EP-0342666-A2 Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same JAPAN ENERGY CORPORATION (JP) 1989-11-23 EP disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed