Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558930 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| Biphenyl SCHEMBL9327587 | 0.88 | PTGS2 (0.53) | SMN1; SMN2MAPTL3MBTL1HPGDPTGS2 | |
| SCHEMBL10489465 | 0.84 | PGR (0.58) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2128162 | 0.84 | PGR (0.58) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL24221611 | 0.82 | LMNA (0.48) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL9405584 | 0.81 | PDPK1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL9192033 | 0.81 | CHRM2 (0.51) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| SCHEMBL9325685 | 0.81 | PDPK1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL4560389 | 0.80 | KMO (0.53) | SMN1; SMN2MAPTL3MBTL1PTGS2HDAC8 | |
| SCHEMBL16186522 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |