Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL10642822 | 0.93 | MAPT (0.45) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL10593278 | 0.81 | MAPT (0.52) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL25280719 | 0.81 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL13212103 | 0.80 | APP (0.57) | ALDH1A1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL1513840 | 0.77 | MEN1 (0.43) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL16069697 | 0.75 | MAPT (0.49) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9819945 | 0.74 | MEN1 (0.41) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| Phosphoric Acid SCHEMBL1513833 | 0.73 | RAB9A (0.42) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9296185 | 0.71 | PIN1 (0.37) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL10962022 | 0.71 | ESR2 (0.42) | MAPTALDH1A1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336600-A | Incubating samples with fluorescent reagent which has observable decrease in emitted light in presence of microorganisms, kits for screening blood, urine, foods, water drugs or cosmetics | BIO MERIEUX (FR) | 1994-08-09 | — | — | US | claimed |
| EP-0207252-B1 | AROMATIC HYDROXY- OR THIOL DERIVATIVES OF CARBONIC-ACID ESTERS AS LIPASE SUBSTRATES | Roche Diagnostics GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |
| US-5091527-A | SUBSTRATE FOR PHOSPHOLIPASE | BOEHRINGER MANNHEIM GMBH (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4988497-A | Diagnostic test for acute pancreatitus or cancer of the pancreas; sensitivity; colorimetry S | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4847376-A | COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |
| US-4719097-A | Phosphates of resorufin derivatives and compositions thereof for the determination of the activity of phosphatases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-01-12 | — | — | US | disclosed |
| EP-0217371-A2 | Phosphates of resorufin derivatives, process for their preparation and their use in the determination of the activity of phosphatases | Roche Diagnostics GmbH (DE) | 1987-04-08 | — | — | EP | disclosed |
| EP-0207252-A2 | Aromatic hydroxy- or thiol derivatives of carbonic-acid esters as lipase substrates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |