Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820046 | 0.82 | GRIN1 (0.36) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9819998 | 0.82 | GAA (0.44) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9819961 | 0.82 | GAA (0.43) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL10351910 | 0.81 | RAB9A (0.34) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9835193 | 0.80 | GAA (0.45) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9820082 | 0.80 | MCL1 (0.35) | MAPTALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL10351889 | 0.79 | GALK1 (0.36) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL1513840 | 0.79 | MEN1 (0.43) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9819887 | 0.77 | MAPT (0.41) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL25280719 | 0.77 | MAPT (0.47) | MEN1KMT2AMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0156347-B1 | GLYCOSIDES OF RESOFURIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF THE ACTIVITY OF GLYCOSIDASES | Roche Diagnostics GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0217371-A2 | Phosphates of resorufin derivatives, process for their preparation and their use in the determination of the activity of phosphatases | Roche Diagnostics GmbH (DE) | 1987-04-08 | — | — | EP | disclosed |
| EP-0210559-A2 | N-Acyldihydroresorufin derivatives, process for their preparation as well as their use for the determination of hydrogen peroxide, peroxidatically active compounds, or peroxidase | Roche Diagnostics GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209875-A1 | Resorufin derivatives and process for their preparation | Roche Diagnostics GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0156347-A2 | Glycosides of resofurin derivatives, method for their preparation and their use in the determination of the activity of glycosidases | Roche Diagnostics GmbH (DE) | 1985-10-02 | — | — | EP | disclosed |