Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465872 | 0.82 | POLB (0.40) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL12550521 | 0.79 | POLB (0.52) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL6256662 | 0.75 | CES2 (0.41) | POLBTSHRALDH1A1CES2CES1 | |
| SCHEMBL1624396 | 0.74 | GPBAR1 (0.44) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL30936965 | 0.73 | GPBAR1 (0.47) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL1820107 | 0.73 | POLB (0.50) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL2097563 | 0.73 | GPBAR1 (0.47) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL6393802 | 0.73 | FSCN1 (0.61) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL10875540 | 0.73 | TSHR (0.45) | POLBTSHRALDH1A1TP53GAA | |
| SCHEMBL11529534 | 0.73 | GPBAR1 (0.43) | POLBTSHRALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334666-A | Vulcanizable elastomer composition comprising epoxy group-containing elastomer, organic compound having at least two -C(X)-NH-C(Y)-bonds (X=O or S, Y=O or S), quaternary ammonium or phosphonium salt, and optionally a urea or thiourea compound | NIPPON ZEON CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0257640-B1 | Vulcanizable elastomer composition | NIPPON ZEON CO (JP) | 1994-03-16 | — | — | EP | disclosed |