SCHEMBL465872

SCHEMBL465872

CN(C)C(=O)N(Cl)c1ccccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
GPBAR1 Q8TDU6 2/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HTT P42858 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
AOC3 Q16853 1/20 0.35
HPGD P15428 1/20 0.35
ESR1 P03372 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
BCL2A1 Q16548 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199099 0.84 CES2 (0.40) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL9327892 0.82 POLB (0.41) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL3157322 0.80 GAA (0.41) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL29524083 0.80 GAA (0.41) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL665305 0.78 ALDH1A1 (0.45) POLBTSHRALDH1A1TP53CES2
SCHEMBL12550521 0.78 POLB (0.52) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL28587764 0.78 ALDH1A1 (0.41) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL6002883 0.78 CES2 (0.41) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL1624396 0.77 GPBAR1 (0.44) POLBGPBAR1TSHRALDH1A1SMN1; SMN2
SCHEMBL10875540 0.77 TSHR (0.45) POLBGPBAR1TSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2551309-B1 ANTIFOULING COATING COMPOSITION AND USE FOR SAME CHUGOKU MARINE PAINTS (JP) 2017-05-17 EP claimed
US-8840910-B2 Antifouling coating composition and uses of the same CHUGOKU MARINE PAINTS, LTD. (JP) 2014-09-23 US claimed
US-20130045264-A1 ANTIFOULING COATING COMPOSITION AND USES OF THE SAME CHUGOKU MARINE PAINTS, LTD. (JP) 2013-02-21 US claimed
EP-2551309-A1 ANTIFOULING COATING COMPOSITION AND USE FOR SAME Chugoku Marine Paints, Ltd. (JP) 2013-01-30 EP claimed
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP claimed
US-8153705-B2 Silyl esters, their use in binder systems and paint compositions and a process for production thereof SIGMAKALON B.V. (NL) 2012-04-10 US claimed
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20100240800-A1 BIOCIDAL ELASTOMERIC COMPOSITIONS AND METHODS OF MAKING THE SAME DASH MULTI-CORP (US) 2010-09-23 US claimed
US-20100209381-A1 COPPER COMPOUND-CONTAINING ANTIFOULING COATING COMPOSITION HAVING IMPROVED SLIME RESISTANCE AND STORAGE STABILITY CHUGOKU MARINE PAINTS, LTD. (JP) 2010-08-19 US claimed
EP-0954965-A1 Controlled release compositions ROHM AND HAAS COMPANY (US) 1999-11-10 EP claimed
EP-0954966-A1 Polymeric controlled release compositions ROHM AND HAAS COMPANY (US) 1999-11-10 EP claimed
EP-0922386-A2 Controlled release compositions ROHM AND HAAS COMPANY (US) 1999-06-16 EP claimed
US-5855654-A APPLYING (DIHYDRO)PYRIDAZINONE COMPOUND ROHM AND HAAS COMPANY (US) 1999-01-05 US claimed
EP-0880892-A1 Controlled release compositions ROHM AND HAAS COMPANY (US) 1998-12-02 EP claimed
US-5833742-A APPLYING ONTO OR INTO MARINE STRUCTURE A MICROBIOCIDES TO INHIBIT THE ORGANISM GROWTH ROHM AND HAAS COMPANY (US) 1998-11-10 US claimed
EP-0856255-A2 Pyridazinones as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-08-05 EP claimed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP claimed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP claimed
US-5221331-A Of a metal salt of hexamethylenedithiocarbamic acid, vehicle, solvent and additives ROHM AND HAAS COMPANY (US) 1993-06-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045264-A1 ANTIFOULING COATING COMPOSITION AND USES OF THE SAME ADRB2, OPRM1, CHRM2 POLB 413/4885GPBAR1 712/4885TSHR 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.