Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326729 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CASP1BRCA1 | |
| SCHEMBL29150713 | 0.72 | TACR1 (0.40) | MEN1KMT2ASMN1; SMN2CASP1BRCA1 | |
| SCHEMBL11416004 | 0.71 | TACR1 (0.43) | TACR1CHRM2CHRM1CHRM3MC4R | |
| SCHEMBL107013 | 0.67 | CNR2 (0.49) | MEN1KMT2AHSD17B10TDP1ESR1 | |
| SCHEMBL157807 | 0.67 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2CASP1BRCA1 | |
| SCHEMBL2589900 | 0.67 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2CASP1BRCA1 | |
| SCHEMBL4565560 | 0.66 | ALDH1A1 (0.41) | SMN1; SMN2NPSR1RAB9AALDH1A1HTT | |
| SCHEMBL4186050 | 0.66 | BCHE (0.44) | MEN1KMT2ATDP1CHRM2CHRM1 | |
| SCHEMBL29664813 | 0.66 | KDM4E (0.35) | KMT2ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL7416028 | 0.66 | TACR1 (0.44) | TACR1CHRM2CHRM1CHRM3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257433-B1 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID CO (US) | 1994-03-23 | — | — | EP | disclosed |
| US-4757146-A | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0257433-A2 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |