SCHEMBL310340

SCHEMBL310340

O=C(O)c1cc2ccccc2c(C(=O)OC(=O)c2nc(C(=O)O)cc3ccccc23)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGFBP3 P17936 6/20 0.48
ALOX15 P16050 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MGAM O43451 1/20 0.40
IGFBP1 P08833 1/20 0.39
IGFBP2 P18065 1/20 0.39
IGFBP4 P22692 1/20 0.39
IGFBP6 P24592 1/20 0.39
IGFBP5 P24593 1/20 0.39
TSHR P16473 2/20 0.38
ACMSD Q8TDX5 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327979 0.86 IGFBP3 (0.52) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL7811857 0.82 ALDH1A1 (0.48) IGFBP3KDM4EALDH1A1KMT2ATSHR
SCHEMBL3205661 0.81 IGFBP3 (0.49) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL4768998 0.75 KDM4E (0.52) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL7591756 0.75 IGFBP3 (0.50) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL1990776 0.74 KDM4E (0.50) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL1202533 0.74 ALDH1A1 (0.50) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL31165745 0.74 MEN1 (0.55) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL6981683 0.74 KDM4E (0.50) IGFBP3ALOX15KDM4EALDH1A1MEN1
SCHEMBL29883306 0.74 KDM4E (0.50) IGFBP3ALOX15KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed