Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 6/20 | 0.70 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA5A | P35218 | 3/20 | 0.63 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.63 |
| ▸ | CA3 | P07451 | 2/20 | 0.63 |
| ▸ | CA6 | P23280 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.63 |
| ▸ | CA4 | P22748 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813838 | 0.89 | SLC16A3 (0.67) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL4758088 | 0.87 | SLC16A3 (0.81) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL14413000 | 0.85 | SLC16A3 (0.61) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL18580402 | 0.83 | NPC1 (0.59) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL9813837 | 0.82 | SLC16A3 (0.58) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL203997 | 0.82 | SLC16A3 (1.00) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL9813833 | 0.82 | SLC16A3 (0.64) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL93260 | 0.81 | SLC16A3 (1.00) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL31222311 | 0.80 | SLC16A3 (0.74) | SLC16A3MAOBCA12CA1CA5A | |
| SCHEMBL4101829 | 0.80 | SLC16A3 (0.74) | SLC16A3MAOBCA12CA1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611912-B1 | NOVEL MONOOXYGENASE VARIANTS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2611912-A2 | NOVEL MONOOXYGENASE VARIANTS | B.R.A.I.N. Biotechnology Research and Information Network AG (DE) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012028709-A2 | NOVEL MONOOXYGENASE VARIANTS | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2426198-A1 | Cytochrome P450 monooxygenase variants | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2012-03-07 | — | — | EP | disclosed |