SCHEMBL203997

SCHEMBL203997

COc1ccc2cc(C(=O)O)c(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 4/20 1.00
ALDH1A1 P00352 7/20 0.78
KDM4E B2RXH2 6/20 0.78
HPGD P15428 5/20 0.78
MAOB P27338 4/20 0.78
GAA P10253 3/20 0.78
CA12 O43570 2/20 0.78
CA2 P00918 2/20 0.78
CA3 P07451 2/20 0.78
CA6 P23280 2/20 0.78
CA7 P43166 2/20 0.78
CA9 Q16790 2/20 0.78
CA14 Q9ULX7 2/20 0.78
CA1 P00915 1/20 0.78
CA5A P35218 1/20 0.78
CA5B Q9Y2D0 1/20 0.78
NPC1 O15118 2/20 0.73
RAB9A P51151 2/20 0.73
POLB P06746 1/20 0.73
GLA P06280 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1366230 0.89 ALDH1A1 (0.81) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL52650 0.89 ALDH1A1 (0.81) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL29963204 0.88 KDM4E (1.00) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL1104931 0.88 ALDH1A1 (1.00) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL978456 0.88 KDM4E (1.00) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL2531452 0.87 ALDH1A1 (0.82) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL11829416 0.87 ALDH1A1 (0.76) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL6687148 0.87 MAOB (0.76) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL455614 0.87 ALDH1A1 (0.76) SLC16A3ALDH1A1KDM4EHPGDMAOB
SCHEMBL28373994 0.86 SLC16A3 (0.80) SLC16A3MAOBCA12CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409871-A Acrylic acid metal salt resin containing coumarin structure, and preparation method and application thereof 中国海洋大学 2025-02-11 CN claimed
US-20240200081-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE Aptacure Therapeutics Limited (CN) 2024-06-20 US claimed
EP-4316495-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE Aptacure Therapeutics Limited (HK) 2024-02-07 EP claimed
CN-117500511-A Nucleic acid molecule conjugates with extended in vivo half-life 安沛治疗有限公司 2024-02-02 CN claimed
CN-115109021-B Synthesis of N- (4-alkoxyphenyl) -7-methoxycoumarin-3-carboxamide, gel prepared by same and application thereof 天津大学 2023-09-12 CN claimed
CN-115308186-B fluorescence-pH biosensor and preparation method and application thereof 广州市乾相生物科技有限公司 2023-01-17 CN claimed
CN-115308186-A fluorescence-pH biosensor and preparation method and application thereof 广州市乾相生物科技有限公司 2022-11-08 CN claimed
WO-2022199685-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE 安沛治疗有限公司 2022-09-29 WO claimed
CN-115109021-A Synthesis of N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide, gel prepared from N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide and application of gel 天津大学 2022-09-27 CN claimed
CN-112898278-B Preparation and application of Sigma-2 fluorescent ligand 广东医科大学 2022-05-13 CN claimed
EP-2303908-B1 FLUORESCENT CYCLIC PEPTIDES, METHODS FOR THE PREPARATION THEREOF, AND USE OF SAID PEPTIDES FOR MEASURING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-07-26 EP claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100317027-A1 SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS POOLE LESLIE B 2010-12-16 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-20080070261-A1 SULFENIC ACID-REACTIVE COMPOUNDS WAKE FOREST UNIVERSITY HEALTH SCIENCES 2008-03-20 US claimed
US-20060084173-A1 Sulfenic acid-reactive compounds and their methods of synthesis and use in detection or isolation of sulfenic acid-containing compounds WAKE FOREST UNIVERSITY HEALTH SCIENCES 2006-04-20 US claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
JP-3109402-A None JP disclosed
US-4159268-A ANTIBIOTICS, MICROBIOCIDES AMERICAN CYANAMID COMPANY (US) 1979-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080070261-A1 SULFENIC ACID-REACTIVE COMPOUNDS QSOX1, SQOR, PRDX1 SLC16A3 3916/4885ALDH1A1 138/4885KDM4E 3725/4885
US-20240200081-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE SOST, FABP1, VEGFA SLC16A3 130/4885ALDH1A1 892/4885KDM4E 4462/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SLC16A3 661/4885ALDH1A1 1901/4885KDM4E 2504/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SLC16A3 222/4885ALDH1A1 1510/4885KDM4E 1109/4885
US-20100317027-A1 SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS QSOX1, SQOR, TST SLC16A3 4077/4885ALDH1A1 323/4885KDM4E 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.