Metobromuron

Metobromuron

SCHEMBL9328486

CON(C)C(=O)Nc1ccc(Br)cc1.O=c1ccc(=O)[nH][nH]1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.80
MEN1 O00255 4/20 0.80
TDP1 Q9NUW8 1/20 0.80
RAB9A P51151 4/20 0.57
PKM P14618 2/20 0.57
HPGD P15428 2/20 0.48
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
NPC1 O15118 3/20 0.40
THRB P10828 1/20 0.40
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.39
ABCB1 P08183 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metobromuron SCHEMBL8536617 0.89 KMT2A (1.00) KMT2AMEN1TDP1RAB9APKM
Metobromuron SCHEMBL53871 0.89 KMT2A (1.00) KMT2AMEN1TDP1RAB9APKM
Metobromuron SCHEMBL20425338 0.86 KMT2A (0.93) KMT2AMEN1TDP1RAB9APKM
Monolinuron SCHEMBL11697559 0.86 PKM (0.80) KMT2AMEN1TDP1RAB9APKM
Metobromuron SCHEMBL28163655 0.85 MEN1 (0.90) KMT2AMEN1TDP1RAB9APKM
Metobromuron SCHEMBL28830153 0.82 KMT2A (0.85) KMT2AMEN1TDP1RAB9APKM
Metobromuron SCHEMBL28163647 0.79 KMT2A (0.78) KMT2AMEN1TDP1RAB9APKM
SCHEMBL10425059 0.75 MEN1 (0.72) KMT2AMEN1TDP1RAB9APKM
SCHEMBL14629465 0.75 RAB9A (0.72) KMT2AMEN1TDP1RAB9APKM
Monolinuron SCHEMBL65568 0.73 RAB9A (1.00) KMT2AMEN1TDP1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584204-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-02 EP claimed
WO-1992020747-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO claimed
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP claimed