Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.56 |
| ▸ | BACE1 | P56817 | 6/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.51 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328525 | 1.00 | REN (0.56) | RENBACE1PSMB1PSMB9PSMB10 | |
| SCHEMBL6803382 | 0.88 | CTSS (0.63) | RENPSMB1PSMB9PSMB10PSMB5 | |
| SCHEMBL6803119 | 0.88 | CTSS (0.63) | RENPSMB1PSMB9PSMB10PSMB5 | |
| SCHEMBL6803127 | 0.88 | CTSS (0.63) | RENPSMB1PSMB9PSMB10PSMB5 | |
| SCHEMBL3840582 | 0.86 | PPARG (0.58) | RENCTSS | |
| SCHEMBL3821796 | 0.84 | PPARA (0.60) | RENCTSS | |
| SCHEMBL3819534 | 0.83 | REN (0.52) | REN | |
| SCHEMBL7447752 | 0.82 | GAA (0.54) | BACE1 | |
| SCHEMBL7447745 | 0.82 | GAA (0.54) | BACE1 | |
| SCHEMBL9329807 | 0.82 | BACE1 (0.49) | BACE1PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298409-A | Of esters, antigen diastereomers which are stable analogs of the unstable ester transition states | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-29 | — | — | US | disclosed |
| US-5190865-A | Antibody-enhanced stereospecific hydrolyses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-03-02 | — | — | US | disclosed |