Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447752 | 1.00 | GAA (0.54) | GAAL3MBTL1PPARGPPARATPSAB1 | |
| SCHEMBL372131 | 0.85 | PPARG (0.51) | GAAL3MBTL1PPARGPPARAALDH1A1 | |
| SCHEMBL7654104 | 0.83 | TPSAB1 (0.56) | GAAL3MBTL1TPSAB1PLGPRSS1 | |
| SCHEMBL15382444 | 0.83 | TPSAB1 (0.53) | GAAL3MBTL1TPSAB1PLGPRSS1 | |
| SCHEMBL7654094 | 0.83 | TPSAB1 (0.56) | GAAL3MBTL1TPSAB1PLGPRSS1 | |
| SCHEMBL6803119 | 0.82 | CTSS (0.63) | PPARGPPARA | |
| SCHEMBL6803382 | 0.82 | CTSS (0.63) | PPARGPPARA | |
| SCHEMBL6803127 | 0.82 | CTSS (0.63) | PPARGPPARA | |
| SCHEMBL9328534 | 0.82 | REN (0.56) | BACE1 | |
| SCHEMBL9328525 | 0.82 | REN (0.56) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |