Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001665 | 0.83 | ALDH1A1 (0.68) | RAB9ANPC1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL13754002 | 0.82 | NPC1 (0.59) | RAB9ARECQLNPC1L3MBTL1CNR1 | |
| SCHEMBL3001664 | 0.81 | ALDH1A1 (0.44) | RAB9ANPC1L3MBTL1CNR1SMN1; SMN2 | |
| SCHEMBL18061243 | 0.81 | GAA (0.47) | RAB9ARECQLNPC1L3MBTL1CNR1 | |
| SCHEMBL19113898 | 0.81 | RAB9A (0.51) | RAB9ARECQLNPC1L3MBTL1CNR1 | |
| SCHEMBL12259023 | 0.79 | HTT (0.44) | RAB9ANPC1GAAALDH1A1KDM4E | |
| SCHEMBL405248 | 0.78 | ALDH1A1 (0.70) | RAB9ARECQLNPC1L3MBTL1CNR1 | |
| SCHEMBL9529702 | 0.78 | CTSV (0.51) | RAB9ARECQLNPC1L3MBTL1CNR1 | |
| SCHEMBL28449044 | 0.76 | HPGD (0.76) | RAB9ANPC1L3MBTL1CNR1SMN1; SMN2 | |
| SCHEMBL14260717 | 0.76 | ALDH1A1 (0.57) | RAB9ARECQLNPC1L3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| CN-1021046-C | PREPARING METHOD FOR NITRIC ESTER DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| US-5010093-A | Vasodilators; cardiovascular disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| CN-1031226-A | Nitrate derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-02-22 | — | — | CN | disclosed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |