Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940406 | 0.90 | EPHX1 (0.49) | ALDH1A1SMN1; SMN2POLBEPHX1MEN1 | |
| SCHEMBL6062528 | 0.79 | EPHX1 (0.48) | ALDH1A1SMN1; SMN2EPHX1MEN1KMT2A | |
| SCHEMBL3717942 | 0.79 | EPHX1 (0.48) | EPHX1MEN1KMT2ACA12CA2 | |
| SCHEMBL1547403 | 0.79 | KDM4E (0.50) | ALDH1A1EPHX1MEN1KMT2ACA12 | |
| SCHEMBL11256841 | 0.78 | EPHX1 (0.39) | ALDH1A1SMN1; SMN2POLBEPHX1MEN1 | |
| SCHEMBL20087451 | 0.77 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBEPHX1MEN1 | |
| SCHEMBL8377830 | 0.76 | ACHE (0.47) | EPHX1MEN1KMT2AGLAGAA | |
| SCHEMBL14240966 | 0.76 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2EPHX1MEN1KMT2A | |
| SCHEMBL5611916 | 0.75 | CASP2 (0.55) | ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL11204612 | 0.74 | EPHX1 (0.47) | ALDH1A1SMN1; SMN2POLBEPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375040-B1 | Process for the preparation of retro-inverso peptides and new intermediates thereof | SCLAVO SPA (IT) | 1994-03-16 | — | — | EP | disclosed |
| US-5116947-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND NEW INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1992-05-26 | — | — | US | disclosed |
| US-5061811-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND 1,3-DIOXANE-4,6-DIONE INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1991-10-29 | — | — | US | disclosed |
| EP-0375040-A2 | Process for the preparation of retro-inverso peptides and new intermediates thereof | SCLAVO S.p.A. (IT) | 1990-06-27 | — | — | EP | disclosed |
| EP-0078952-B1 | N-AMINOALKYL IODOTHYRONINE DERIVATIVES, IODOTHYRONINE IMMUNOGENS AND ANTIBODIES | MILES LABORATORIES, INC. (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0087564-A1 | Specific binding assay method, reagent system and labelled conjugate for use in this method | MILES LABORATORIES, INC. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4399121-A | Iodothyronine immunogens and antibodies | MILES LABORATORIES, INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0079489-A1 | Methotrexate-labeled iodothyronine conjugates and method, reagent means and test device for the determination of iodothyronine in or iodothyronine uptake of a liquid sample | MILES LABORATORIES, INC. (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0078952-A1 | N-aminoalkyl iodothyronine derivatives, iodothyronine immunogens and antibodies | MILES LABORATORIES, INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4358604-A | ANTIBODIES-USEFUL IN IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1982-11-09 | — | — | US | disclosed |