SCHEMBL9328858

SCHEMBL9328858

CC(=O)N(N)c1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.46
TDP1 Q9NUW8 5/20 0.46
ALDH1A1 P00352 5/20 0.46
ALOX15 P16050 3/20 0.46
MAPK1 P28482 2/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GFER P55789 2/20 0.41
RECQL P46063 2/20 0.41
PSMD14 O00487 1/20 0.41
MAPT P10636 4/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 2/20 0.39
DHFR P00374 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2C19 P33261 3/20 0.38
CYP1A2 P05177 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP2C9 P11712 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036611 0.82 ALDH1A1 (0.46) TDP1ALDH1A1TSHRMAPTRAB9A
SCHEMBL5663915 0.82 ESR1 (0.41) CYP3A4ALDH1A1ALOX15TSHRL3MBTL1
SCHEMBL8556395 0.81 ALDH1A1 (0.46) ALDH1A1MAPK1TSHRSMN1; SMN2KDM4E
SCHEMBL754646 0.80 TSHR (0.45) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL5736585 0.80 APP (0.41) ALDH1A1MAPTNPC1KMT2AAPAF1
SCHEMBL10441524 0.80 MT-CO2 (0.46) CYP3A4TDP1ALDH1A1ALOX15TSHR
SCHEMBL7032266 0.80 MAPT (0.42) ALDH1A1TSHRMAPTRAB9ANPC1
SCHEMBL26108874 0.79 CYP3A4 (0.48) CYP3A4TDP1ALDH1A1ALOX15MAPK1
SCHEMBL9233431 0.79 ALDH1A1 (0.42) CYP3A4TDP1ALDH1A1ALOX15MAPK1
SCHEMBL109764 0.79 NPSR1 (0.52) CYP3A4TDP1ALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5366837-A Image receiving sheet and image transferring method employing the image receiving sheet BROTHER KOGYO KABUSHIKI KAISHA (JP) 1994-11-22 US disclosed
EP-0203613-A2 Light-sensitive material containing microcapsules and image-recording method using the same FUJI PHOTO FILM CO., LTD. (JP) 1986-12-03 EP disclosed
EP-0154293-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1985-09-11 EP disclosed
EP-0147765-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-07-10 EP disclosed
EP-0023780-A1 Silver halide emulsions containing a nucleating agent, photographic elements, film unit and processes for the production of direct positive images EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-02-11 EP disclosed