SCHEMBL7036611

SCHEMBL7036611

CC(=O)N(N)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
RAB9A P51151 2/20 0.46
TSHR P16473 1/20 0.42
LMNA P02545 4/20 0.42
KDM4E B2RXH2 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MAPT P10636 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
HTT P42858 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALOX5 P09917 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
PKM P14618 2/20 0.37
ATM Q13315 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11319421 0.82 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2RAB9ATSHRLMNA
SCHEMBL11030370 0.82 ALOX5 (0.46) ALDH1A1SMN1; SMN2RAB9ATSHRLMNA
SCHEMBL9328858 0.82 CYP3A4 (0.46) ALDH1A1SMN1; SMN2RAB9ATSHRLMNA
SCHEMBL5663915 0.82 ESR1 (0.41) ALDH1A1RAB9ATSHRLMNAKDM4E
SCHEMBL5736585 0.80 APP (0.41) ALDH1A1MAPTHPGDKMT2A
SCHEMBL754646 0.80 TSHR (0.45) ALDH1A1TSHRCES2CES1MAPT
SCHEMBL7032266 0.80 MAPT (0.42) ALDH1A1SMN1; SMN2RAB9ATSHRLMNA
SCHEMBL10441524 0.80 MT-CO2 (0.46) ALDH1A1TSHRLMNAKDM4ECES2
SCHEMBL109764 0.79 NPSR1 (0.52) ALDH1A1SMN1; SMN2RAB9ATSHRCES2
SCHEMBL11314703 0.78 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2RAB9ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
CN-115894326-B 2, 3-Hydrogen substituted aminoindole derivative, preparation method and application thereof 佛山大学 2025-02-11 CN disclosed
CN-115894326-A 2,3-hydrogen substituted aminoindole derivative, preparation method and application thereof 佛山科学技术学院 2023-04-04 CN disclosed
CN-109467528-B Synthesis method of 1-aminoindole derivative 佛山科学技术学院 2020-11-06 CN disclosed
CN-104262284-A 2-amino-1, 3, 4-oxadiazole compound and preparation method thereof UNIV SHANGHAI 2015-01-07 CN disclosed
CN-103282402-A Anaerobically curable composition THREE BOND CO LTD 2013-09-04 CN disclosed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP disclosed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO disclosed