Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842374 | 0.87 | LMNA (0.49) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL841079 | 0.87 | LMNA (0.49) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL9331288 | 0.86 | MEN1 (0.46) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL9328442 | 0.86 | HPGD (0.50) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL3854880 | 0.81 | EPOR (0.54) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL3854879 | 0.81 | EPOR (0.54) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL3632576 | 0.81 | L3MBTL1 (0.54) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL28162835 | 0.81 | LMNA (0.50) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL842164 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1LMNARAB9AL3MBTL1 | |
| SCHEMBL842166 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1LMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387605-B1 | Process for the stereoselective preparation of optically active S,S or R,R-beta-aminoalcohols | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0387605-A2 | Process for the stereoselective preparation of optically active S,S or R,R-beta-aminoalcohols | BAYER AG (DE) | 1990-09-19 | — | — | EP | disclosed |