Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328990 | 0.92 | CYP2D6 (0.43) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9330744 | 0.92 | CYP1A2 (0.58) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9327602 | 0.87 | CYP2D6 (0.43) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9327573 | 0.86 | GLA (0.46) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL12835292 | 0.85 | CYP2D6 (0.51) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9328912 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9328593 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9327921 | 0.84 | CYP2D6 (0.44) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9328729 | 0.84 | CYP2D6 (0.49) | CYP1A2CYP1A1CYP1B1PRKDCHPGD | |
| SCHEMBL9328862 | 0.84 | ALDH1A1 (0.51) | CYP1A2CYP1A1CYP1B1PRKDCHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | claimed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | claimed |
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5238954-A | Antitumor agents | THE UPJOHN COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | disclosed |