Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306475 | 0.71 | FDPS (0.32) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL10697591 | 0.71 | FDPS (0.39) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL10936504 | 0.70 | FDPS (0.34) | FDPSGGPS1 | |
| SCHEMBL11301592 | 0.65 | MMP1 (0.35) | FDPS | |
| SCHEMBL3901347 | 0.65 | FDPS (0.50) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL9442591 | 0.64 | FDPS (0.37) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL10764756 | 0.64 | LMNA (0.33) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL1768259 | 0.61 | FDPS (0.43) | FDPSGGPS1 | |
| SCHEMBL6296955 | 0.61 | FDPS (0.43) | FDPSGGPS1 | |
| SCHEMBL246809 | 0.61 | FDPS (0.43) | FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300387-B1 | Phenyl alkenylcarboxylic acids and their esters | BASF AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0300387-A2 | Phenyl alkenylcarboxylic acids and their esters | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4440779-A | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |