SCHEMBL9329029

SCHEMBL9329029

Cc1ccccc1COC(=O)c1ccc(C(C)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.47
MAPT P10636 7/20 0.45
RAB9A P51151 5/20 0.45
NPC1 O15118 3/20 0.45
PPARG P37231 1/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
PKM P14618 1/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
ADORA2A P29274 1/20 0.43
LMNA P02545 3/20 0.42
RXFP1 Q9HBX9 2/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9328616 0.84 MAOB (0.46) MAOBMAPTRAB9ANPC1PPARG
SCHEMBL9328542 0.83 KMT2A (0.46) MAPTRAB9ANPC1PPARGKMT2A
SCHEMBL3628980 0.83 ESR1 (0.61) MAOBMAPTRAB9ANPC1PPARG
SCHEMBL471706 0.83 PPARG (0.61) MAOBMAPTRAB9ANPC1PPARG
SCHEMBL9329226 0.82 MAOB (0.68) MAOBMAPTRAB9ANPC1PPARG
SCHEMBL9329147 0.81 KMT2A (0.67) MAPTRAB9ANPC1KMT2AALDH1A1
SCHEMBL6394260 0.79 ESR1 (0.56) MAOBMAPTRAB9ANPC1PPARG
SCHEMBL14039347 0.78 CA1 (0.61) MAPTRAB9ANPC1KMT2AALDH1A1
SCHEMBL9329526 0.77 KMT2A (0.61) MAPTRAB9ANPC1KMT2APOLB
SCHEMBL4231829 0.76 ALDH1A1 (0.52) MAOBMAPTRAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332675-A Liquid crystals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-26 US disclosed
EP-0289307-B1 OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-5019298-A Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-28 US disclosed
EP-0289307-A2 Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-02 EP disclosed