Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329146 | 1.00 | CNR1 (0.42) | CNR1CNR2ITGA4ITGB7KMT2A | |
| SCHEMBL9329153 | 1.00 | CNR1 (0.42) | CNR1CNR2ITGA4ITGB7KMT2A | |
| SCHEMBL5349503 | 0.77 | MAPT (0.43) | CNR1CNR2KMT2AMEN1MAPT | |
| SCHEMBL9328997 | 0.73 | CHRM2 (0.47) | CNR2ITGA4ITGB7KMT2ASMN1; SMN2 | |
| SCHEMBL9219191 | 0.73 | CHRM2 (0.47) | CNR2ITGA4ITGB7KMT2ASMN1; SMN2 | |
| SCHEMBL9219188 | 0.73 | CHRM2 (0.47) | CNR2ITGA4ITGB7KMT2ASMN1; SMN2 | |
| SCHEMBL9329061 | 0.72 | MAPT (0.40) | ITGA4ITGB7KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9398875 | 0.72 | MAPT (0.41) | ITGA4ITGB7KMT2AMEN1MAPT | |
| SCHEMBL14317672 | 0.70 | CYP1A2 (0.47) | ITGA4ITGB7SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9520568 | 0.69 | SLC6A3 (0.41) | CNR1CNR2ITGA4ITGB7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0377532-B1 | THIOFORMAMIDE DERIVATIVES | MAY AND BAKER LIMITED (GB) | 1992-07-29 | — | — | EP | disclosed |
| US-5104883-A | Cardiovascular, respiratory, gastrointestirol, urogenital disorders; baldness; premature labor | MAY & BAKER LIMITED (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |