Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083398 | 0.87 | RAPGEF4 (0.59) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL4844624 | 0.82 | RAPGEF4 (0.46) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL6660827 | 0.81 | HPGD (0.41) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL9327344 | 0.81 | LMNA (0.44) | ALDH1A1RECQLKDM4EGAAMAPT | |
| Sulfuric Acid SCHEMBL7811899 | 0.81 | LMNA (0.55) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL7564333 | 0.81 | RAPGEF4 (0.51) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL13901546 | 0.81 | CYP2D6 (0.46) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL13901754 | 0.81 | ALDH1A1 (0.47) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL9448742 | 0.80 | RAPGEF4 (0.44) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E | |
| SCHEMBL8960299 | 0.79 | RAPGEF4 (0.51) | RAPGEF4ALDH1A1L3MBTL1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413230-B1 | Nitroaniline sulphonic acids and process for preparing phenylenediamino sulphonic acids | BASF AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0324373-B1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5260431-A | Nitroanilinesulfonic acids and the preparation of phenylenediaminesulfonic acids | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0324372-B1 | WATER SOLUBLE 2-NAPHTHOL AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5206426-A | Phenylene diamines and process for the preparation of phenylene diamines | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0396077-B1 | PHENYLENE DIAMINES AND A PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-5117050-A | PHENYLENE DIAMINES AND PROCESS FOR THE PREPARATION OF PHENYLENE DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-5047515-A | Monoazo Dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0413230-A1 | Nitroaniline sulphonic acids and process for preparing phenylenediamino sulphonic acids | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0396077-A1 | Phenylene diamines and a process for their preparation | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0324373-A2 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0324372-A2 | Water soluble 2-naphthol azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-19 | — | — | EP | disclosed |