Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Phenylsulfonyl)Benzene SCHEMBL29450723 | 0.73 | HTR6 (1.00) | HTR6CA1CA2TDP1ALDH1A1 | |
| Disulfone SCHEMBL8427811 | 0.73 | HTR6 (0.65) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29473549 | 0.73 | HTR6 (1.00) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29775288 | 0.73 | HTR6 (1.00) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL30255 | 0.73 | HTR6 (1.00) | HTR6CA1CA2TDP1ALDH1A1 | |
| Disulfone SCHEMBL493732 | 0.73 | HTR6 (0.65) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.73 | HTR6 (1.00) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL25435825 | 0.71 | HTR6 (0.93) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL9797473 | 0.71 | HTR6 (0.93) | HTR6CA1CA2TDP1ALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL1067504 | 0.71 | HTR6 (0.93) | HTR6CA1CA2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006587-B1 | SULFONYL UREAS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | claimed |
| US-5338658-A | Nucleation agent | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |
| US-4157395-A | TREATMENT OF DIABETES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-05 | — | — | US | disclosed |