SCHEMBL9329423

SCHEMBL9329423

O=C(O)c1ccc(Cc2ccccc2)c(C(=O)O)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.45
MGAM O43451 1/20 0.44
RNASEH1 O60930 1/20 0.44
KDM4E B2RXH2 2/20 0.44
TSHR P16473 2/20 0.44
ALOX15 P16050 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTPN1 P18031 2/20 0.41
PTPN2 P17706 1/20 0.41
PTPN6 P29350 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ECE1 P42892 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28613561 0.80 PLA2G10 (0.46) MEN1KMT2ABCL2BCL2L1
SCHEMBL19857481 0.78 KDM4E (0.45) HCAR2MGAMKDM4ETSHRALOX15
SCHEMBL29110058 0.77 KDM4E (0.43) MGAMKDM4ETSHRALOX15ACMSD
SCHEMBL2960936 0.74 KDM4E (0.64) RNASEH1KDM4ETSHRALOX15PTPN1
SCHEMBL26969215 0.73 ALDH1A1 (0.69) MGAMRNASEH1KDM4EPTPN1PTPN2
SCHEMBL23529950 0.72 KDM4E (0.39) MGAMKDM4ETSHRALOX15ACMSD
Hydrochloric Acid SCHEMBL8126278 0.72 KDM4E (0.62) RNASEH1KDM4ETSHRALOX15PTPN1
SCHEMBL5134009 0.72 KDM4E (0.39) MGAMKDM4ETSHRALOX15ACMSD
SCHEMBL11814351 0.71 BRD4 (0.71) HCAR2KDM4ETSHRALOX15ACMSD
SCHEMBL947154 0.69 HCAR2 (0.45) HCAR2RNASEH1KDM4ETSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US disclosed