Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335337 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CA14ALOX15CA12 | |
| SCHEMBL2912889 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CA14ALOX15CA12 | |
| SCHEMBL422851 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL6933551 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA14ALOX15CA12 | |
| SCHEMBL14375225 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1ALOX15KMT2AMGAM | |
| SCHEMBL10485422 | 0.80 | CA1 (0.36) | SMN1; SMN2ALDH1A1CA14ALOX15MMP2 | |
| SCHEMBL16502244 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA14ALOX15MMP2 | |
| SCHEMBL23803859 | 0.78 | CA1 (0.36) | SMN1; SMN2ALDH1A1CA14ALOX15CA12 | |
| SCHEMBL2202923 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1CA14ALOX15CA12 | |
| SCHEMBL9788243 | 0.78 | MGAM (0.46) | SMN1; SMN2ALDH1A1CA14ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560550-B2 | Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives | RFS PHARMA, LLC (US) | 2009-07-14 | — | — | US | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0912467-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000375-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1998-01-08 | — | — | WO | claimed |
| US-20240360068-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND THEIR USES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-10-31 | — | — | US | disclosed |
| US-20230265041-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-24 | — | — | US | disclosed |
| US-11687003-B2 | Negative resist pattern-forming method, and composition for upper layer film formation | JSR CORPORATION (JP) | 2023-06-27 | — | — | US | disclosed |
| EP-3365380-B1 | VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING | AKDENIZ CHEMSON ADDITIVES AG (AT) | 2023-04-26 | — | — | EP | disclosed |
| US-11608309-B2 | Curcumin analogues as zinc chelators and their uses | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-03-21 | — | — | US | disclosed |
| US-11542389-B2 | Vinyl chloride polymers and compositions for additive manufacturing | AKDENIZ CHEMSON ADDITIVES AG (AT) | 2023-01-03 | — | — | US | disclosed |
| US-20210053905-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND THEIR USES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-25 | — | — | US | disclosed |
| US-20210017374-A1 | VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING | AKDENIZ CHEMSON ADDITIVES AG (AT) | 2021-01-21 | — | — | US | disclosed |
| US-5424421-A | Synthesis of carminic acid and principal intermediates | EUROPEAN COLOUR PLC (GB) | 1995-06-13 | — | — | US | disclosed |
| EP-0602027-A1 | SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. | EUROP COLOUR PLC (GB) | 1994-06-22 | — | — | EP | disclosed |
| EP-0297752-B1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALCOHOL | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5144057-A | Process for the production of 3-oxocarboxylic acid esters | LONZA LTD. (CH) | 1992-09-01 | — | — | US | disclosed |
| WO-1992001664-A1 | SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES | EUROPEAN COLOUR PLC (GB) | 1992-02-06 | — | — | WO | disclosed |
| US-4916252-A | OPTICALLY ACTIVE PHOSPHINE-RUTHENIUM HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0297752-A2 | Process of preparing optically active alcohol | Takasago International Corporation (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4107133-A | ORGANIC PIGMENT, ORGANOSILANE OR ORGANOTITANIUM COMPOUND | DAINIPPON INK & CHEMICALS, INC. (JP) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265041-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES | NFRKB, NFKBIA, NFKB1 | SMN1; SMN2 4301/4885ALDH1A1 1929/4885CA14 2432/4885 |
| US-11608309-B2 | Curcumin analogues as zinc chelators and their uses | NFKBIA, NFKB1, NFKB2 | SMN1; SMN2 3825/4885ALDH1A1 966/4885CA14 2192/4885 |
| US-20210053905-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND THEIR USES | NFKBIA, NFKB1, NFKB2 | SMN1; SMN2 3825/4885ALDH1A1 966/4885CA14 2192/4885 |
| US-20240360068-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND THEIR USES | NFKBIA, NFKB1, NFKB2 | SMN1; SMN2 3825/4885ALDH1A1 966/4885CA14 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.