Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335337 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1ALOX15KMT2ACA14 | |
| SCHEMBL932950 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1ALOX15KMT2ACA14 | |
| Hydrochloric Acid SCHEMBL11145353 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2ACA14MMP2 | |
| SCHEMBL26657825 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1KMT2ACA14MMP2 | |
| SCHEMBL26657839 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1KMT2ACA14MMP2 | |
| SCHEMBL269877 | 0.76 | FFAR3 (0.43) | ALDH1A1ALOX15KMT2ATP53 | |
| SCHEMBL422851 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2ACA14MMP2 | |
| SCHEMBL28523 | 0.76 | FFAR3 (0.43) | ALDH1A1ALOX15KMT2ATP53 | |
| SCHEMBL1012864 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ALOX15KMT2AMGAMGAA | |
| SCHEMBL25278592 | 0.74 | FFAR3 (0.40) | ALDH1A1ALOX15KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064122-A | Hydroxy-substituted cephalosporins | ISHIMARU TOSHIYASU | 1977-12-20 | — | — | US | claimed |
| JP-7316147-A | — | — | None | — | — | JP | disclosed |
| US-20210069173-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | ALTER DOMUS (US) LLC | 2021-03-11 | — | — | US | disclosed |
| WO-2019143508-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | CODY LABORATORIES, INC. (US) | 2019-07-25 | — | — | WO | disclosed |
| US-20190224185-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | CODY LABORATORIES, INC. | 2019-07-25 | — | — | US | disclosed |
| US-20190224184-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | ALTER DOMUS (US) LLC | 2019-07-25 | — | — | US | disclosed |
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-7855296-B1 | Method for synthesizing 2-carbomethoxytropinone | CODY LABORATORIES, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2181089-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | Ratiopharm GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-5948933-A | THERAPY FOR DRUG ABRUSE | ORGANIX, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999002526-A1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| JP-H07316147-A | KETOCOUMARIN DERIVATIVE AND PHOTOSENSITIZATION PIGMENT FOR PHOTOPOLYMER COMPRISING SUCH DERIVATIVE | NIPPON KANKO SHIKISO KENKYUSHO:KK | 1995-12-05 | — | — | JP | disclosed |
| US-4960907-A | Partially saponifying; delarboxylating diesters; optional ketalization | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0276204-A2 | Pyridine gametocides | Monsanto Company (US) | 1988-07-27 | — | — | EP | disclosed |
| US-4747871-A | 2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides | MONSANTO COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0022482-B1 | PROCESS FOR PREPARING 4-HYDROXY-3-METHYL-2-(2-PROPYNYL)-2-CYCLOPENTENOLONE; A GAMMA-DIKETONE COMPOUND AND SUBSTITUTED ACETONEDICARBOXYLIC ESTERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-09-14 | — | — | EP | disclosed |
| US-4343953-A | STARTING WITH A 3-OXO-GLUTARATE AND 3-CHLOROPROPYNE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0022482-A2 | Process for preparing 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentenolone; a gamma-diketone compound and substituted acetonedicarboxylic esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4229582-A | Process for the preparation of sterically uniform, natural 6-thiatetracycline derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | HMGCR, DPYD, FDPS | SMN1; SMN2 4585/4885ALDH1A1 671/4885ALOX15 603/4885 |
| US-20190224185-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | CES2, SLC6A3, BCHE | SMN1; SMN2 1177/4885ALDH1A1 2326/4885ALOX15 3717/4885 |
| US-20210069173-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | CES2, SLC6A3, BCHE | SMN1; SMN2 1177/4885ALDH1A1 2326/4885ALOX15 3717/4885 |
| US-20190224184-A1 | PREPARATION OF (-)-COCAINE HYDROCHLORIDE | CES2, SLC6A3, BCHE | SMN1; SMN2 1177/4885ALDH1A1 2326/4885ALOX15 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.