Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621258 | 0.91 | MAOB (0.48) | MAOBADORA2BMAOAALOX15ALOX12 | |
| SCHEMBL9329983 | 0.76 | POLB (0.53) | MAOBMAOAKMT2A | |
| SCHEMBL8311797 | 0.76 | MAOB (0.49) | MAOBADORA2BMAOAACHEALOX15 | |
| SCHEMBL8082564 | 0.74 | MEN1 (0.49) | KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL10516530 | 0.73 | MAOB (0.56) | MAOBADORA2BMAOAACHEALOX15 | |
| SCHEMBL8122069 | 0.73 | MAOB (0.48) | MAOBADORA2BMAOAALOX15ALOX12 | |
| SCHEMBL8122057 | 0.73 | MAOB (0.48) | MAOBADORA2BMAOAALOX15ALOX12 | |
| SCHEMBL9329505 | 0.72 | MAOB (0.48) | MAOBADORA2BMAOAACHE | |
| SCHEMBL10517674 | 0.71 | MAOB (0.57) | MAOBADORA2BMAOAACHEALOX15 | |
| SCHEMBL9331303 | 0.70 | TOP1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |