Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311797 | 0.90 | MAOB (0.49) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL8122057 | 0.89 | MAOB (0.48) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL8621258 | 0.82 | MAOB (0.48) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL10682794 | 0.77 | MAOB (0.35) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL8628828 | 0.73 | ALOX12 (0.50) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL9329500 | 0.73 | MAOB (0.46) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL11033235 | 0.72 | MAPT (0.40) | MAOB | |
| SCHEMBL11281619 | 0.72 | MAOB (0.42) | MAOBMAOAADORA2BTACR3 | |
| SCHEMBL11247457 | 0.70 | MAOB (0.39) | MAOBMAOAADORA2BTACR3HDAC6 | |
| SCHEMBL11249099 | 0.70 | KDM4E (0.40) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366641-B1 | Novel antimicrobial quinolonyl lactam esters | NORWICH EATON PHARMA (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0997466-A1 | Novel antimicrobial lactam-quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0775114-B1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | PROCTER & GAMBLE (US) | 2000-03-22 | — | — | EP | disclosed |
| CN-1159809-A | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds | PROCTER & GAMBLE (US) | 1997-09-17 | — | — | CN | disclosed |
| US-5656623-A | BACTERICIDES; ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5648346-A | Antimicrobial carbacephem-quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5646139-A | TREATING AND PREVENTING INFECTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5637580-A | ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0775145-A1 | PROCESS FOR MAKING QUINOLONYL LACTAM ANTIMICROBIALS AND NOVEL INTERMEDIATE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0775114-A1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0525057-A4 | ANTIMICROBIAL QUINOLONYL LACTAMS | — | 1993-04-07 | — | — | EP | disclosed |
| EP-0525057-A1 | ANTIMICROBIAL QUINOLONYL LACTAMS | Norwich Eaton Pharmaceuticals, Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-5180719-A | Microbiocides | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1993-01-19 | — | — | US | disclosed |
| WO-1991016327-A1 | ANTIMICROBIAL QUINOLONYL LACTAMS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1990004594-A1 | NOVEL ANTIMICROBIAL QUINOLONYL LACTAM ESTERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-05-03 | — | — | WO | disclosed |
| WO-1990004595-A1 | NOVEL ANTIMICROBIAL FLUOROQUINOLONYL CEPHEMS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-05-03 | — | — | WO | disclosed |
| EP-0366193-A2 | Novel antimicrobial quinolonyl lactams | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0366640-A2 | Novel antimicrobial fluoroquinolonyl cephems | Norwich-Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0366641-A2 | Novel antimicrobial quinolonyl lactam esters | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |