Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314839 | 0.87 | POLB (0.70) | POLBRAB9AGPR35MAOBMAOA | |
| SCHEMBL9329500 | 0.76 | MAOB (0.46) | MAOBMAOAKMT2A | |
| SCHEMBL8082564 | 0.72 | MEN1 (0.49) | POLBHTTKMT2AKDM4EMEN1 | |
| SCHEMBL6490749 | 0.72 | MAOB (0.72) | POLBRAB9AGPR35MAOBMAOA | |
| SCHEMBL9329987 | 0.71 | NPC1 (0.53) | RAB9AGPR35MAOBMAOANPC1 | |
| SCHEMBL9331303 | 0.71 | TOP1 (0.50) | POLBKDM4EGAAALDH1A1 | |
| SCHEMBL29628919 | 0.70 | GPR35 (0.76) | GPR35MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL980268 | 0.70 | GPR35 (0.76) | GPR35MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL15744786 | 0.70 | ALDH1A1 (0.74) | POLBGPR35KMT2AKDM4EMEN1 | |
| SCHEMBL34468754 | 0.69 | POLB (1.00) | POLBRAB9AGPR35MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |