Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Anthraquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.92 |
| ▸ | CDC25B | P30305 | 3/20 | 0.92 |
| ▸ | MAOA | P21397 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | APAF1 | O14727 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | TDP2 | O95551 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | S100A4 | P26447 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.73 |
| ▸ | TERT | O14746 | 1/20 | 0.73 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.73 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28112335 | 0.96 | MEN1 (0.86) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL14943 | 0.96 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL1901249 | 0.96 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL29358690 | 0.96 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL11300863 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL10905960 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL240670 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL7205968 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL8081485 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL20299926 | 0.92 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585395-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN CHEMICAL COMPANY (US) | 1994-03-09 | — | — | EP | claimed |
| WO-1992019586-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN KODAK COMPANY (US) | 1992-11-12 | — | — | WO | claimed |
| US-5117014-A | Bromination | EASTMAN KODAK COMPANY (US) | 1992-05-26 | — | — | US | claimed |
| US-12544322-B2 | Dyeing composition comprising an anthraquinone cationic direct dye, a polyol, an anionic surfactant and a nonionic polysaccharide | L'ORÉAL (FR) | 2026-02-10 | — | — | US | disclosed |
| WO-2025132917-A1 | PROCESS FOR DYEING THE HAIR USING A LIGHTENING COMPOSITION AND A DYEING COMPOSITION COMPRISING A DIRECT DYE, AN AROMATIC COMPOUND AND A HYDROXYLATED ALIPHATIC SOLVENT | L'OREAL (FR) | 2025-06-26 | — | — | WO | disclosed |
| US-12226502-B2 | Dyeing composition comprising a specific anthraquinone cationic direct dye, a cationic surfactant, an amphoteric or zwitterionic surfactant and a fatty alcohol | L'OREAL (FR) | 2025-02-18 | — | — | US | disclosed |
| US-20230363994-A1 | DYEING COMPOSITION COMPRISING AN ANTHRAQUINONE CATIONIC DIRECT DYE, A POLYOL, AN ANIONIC SURFACTANT AND A NONIONIC POLYSACCHARIDE | L'OREAL (FR) | 2023-11-16 | — | — | US | disclosed |
| US-20230270643-A1 | DYEING AND/OR LIGHTENING COMPOSITION COMPRISING AN ANTHRAQUINONE CATIONIC DIRECT DYE, A FATTY SUBSTANCE, A CHEMICAL OXIDIZING AGENT AND A BASIFYING AGENT AND/OR AN OXIDATION DYE PRECURSOR | L'OREAL (FR) | 2023-08-31 | — | — | US | disclosed |
| US-20230240955-A1 | DYEING COMPOSITION COMPRISING A SPECIFIC ANTHRAQUINONE CATIONIC DIRECT DYE, A CATIONIC SURFACTANT, AN AMPHOTERIC OR ZWITTERIONIC SURFACTANT AND A FATTY ALCOHOL | L'OREAL (FR) | 2023-08-03 | — | — | US | disclosed |
| EP-4171481-A1 | DYEING COMPOSITION COMPRISING A SPECIFIC ANTHRAQUINONE CATIONIC DIRECT DYE, A CATIONIC SURFACTANT, AN AMPHOTERIC OR ZWITTERIONIC SURFACTANT AND A FATTY ALCOHOL | L'OREAL (FR) | 2023-05-03 | — | — | EP | disclosed |
| EP-4171480-A1 | DYEING COMPOSITION COMPRISING AN ANTHRAQUINONE CATIONIC DIRECT DYE, A POLYOL, AN ANIONIC SURFACTANT AND A NONIONIC POLYSACCHARIDE | L'OREAL (FR) | 2023-05-03 | — | — | EP | disclosed |
| EP-0585395-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN CHEMICAL COMPANY (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992019586-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN KODAK COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5117014-A | Bromination | EASTMAN KODAK COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12226502-B2 | Dyeing composition comprising a specific anthraquinone cationic direct dye, a cationic surfactant, an amphoteric or zwitterionic surfactant and a fatty alcohol | KRT18, DSG1, ANXA5 | MEN1 1865/4885KMT2A 2330/4885CDC25B 4277/4885 |
| US-20230363994-A1 | DYEING COMPOSITION COMPRISING AN ANTHRAQUINONE CATIONIC DIRECT DYE, A POLYOL, AN ANIONIC SURFACTANT AND A NONIONIC POLYSACCHARIDE | KRT18, DSG1, KRTCAP2 | MEN1 1244/4885KMT2A 2015/4885CDC25B 4375/4885 |
| US-20230240955-A1 | DYEING COMPOSITION COMPRISING A SPECIFIC ANTHRAQUINONE CATIONIC DIRECT DYE, A CATIONIC SURFACTANT, AN AMPHOTERIC OR ZWITTERIONIC SURFACTANT AND A FATTY ALCOHOL | KRT18, DSG1, ANXA5 | MEN1 1865/4885KMT2A 2330/4885CDC25B 4277/4885 |
| US-12544322-B2 | Dyeing composition comprising an anthraquinone cationic direct dye, a polyol, an anionic surfactant and a nonionic polysaccharide | KRT18, DSG1, S100A10 | MEN1 1264/4885KMT2A 1905/4885CDC25B 3243/4885 |
| US-20230270643-A1 | DYEING AND/OR LIGHTENING COMPOSITION COMPRISING AN ANTHRAQUINONE CATIONIC DIRECT DYE, A FATTY SUBSTANCE, A CHEMICAL OXIDIZING AGENT AND A BASIFYING AGENT AND/OR AN OXIDATION DYE PRECURSOR | KRT18, SQOR, FASN | MEN1 1750/4885KMT2A 2167/4885CDC25B 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.