Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 5/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331226 | 0.88 | PANK3 (0.47) | CYP2C9CYP2C19HPGDSPANK3CYP1A2 | |
| SCHEMBL9329368 | 0.85 | CYP2C9 (0.57) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9329277 | 0.80 | HPGDS (0.46) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9328754 | 0.79 | MEN1 (0.60) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9329461 | 0.78 | MEN1 (0.48) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9328726 | 0.77 | HIF1A (0.54) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9331727 | 0.77 | MEN1 (0.50) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9329229 | 0.77 | MEN1 (0.47) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL9329984 | 0.76 | RAB9A (0.55) | CYP2C9CYP2C19MEN1KMT2AALOX15 | |
| SCHEMBL6185761 | 0.76 | ACHE (0.56) | HPGDSEIF4EDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5010093-A | Vasodilators; cardiovascular disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |