Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333191 | 1.00 | EPHX1 (0.43) | EPHX1BCHECHRM3SCN1ASCN2A | |
| SCHEMBL9333378 | 0.85 | SMN1; SMN2 (0.44) | EPHX1BCHEMEN1KMT2A | |
| SCHEMBL9344119 | 0.82 | MAPK1 (0.40) | MEN1KMT2ALMNADRD2HTR2A | |
| SCHEMBL9333285 | 0.82 | EPHX1 (0.39) | EPHX1BCHECHRM3SCN1ASCN2A | |
| SCHEMBL9330860 | 0.82 | EPHX1 (0.39) | EPHX1BCHECHRM3SCN1ASCN2A | |
| SCHEMBL9329933 | 0.81 | UGT8 (0.36) | EPHX1BCHECHRM3SCN1ASCN2A | |
| SCHEMBL9333289 | 0.81 | UGT8 (0.36) | EPHX1BCHECHRM3SCN1ASCN2A | |
| SCHEMBL9333212 | 0.80 | BCHE (0.44) | EPHX1BCHELMNA | |
| SCHEMBL9344169 | 0.80 | TSHR (0.39) | MEN1KMT2ALMNAPKM | |
| SCHEMBL4889799 | 0.79 | GSR (0.39) | CHRM3SCN1ASCN2ASCN3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |