Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333289 | 1.00 | UGT8 (0.36) | UGT8CHRM3BCHEEPHX1TPSAB1 | |
| SCHEMBL9346184 | 0.84 | EPHX1 (0.41) | EPHX1KMT2AGSK3BMAPTSMN1; SMN2 | |
| SCHEMBL9329950 | 0.81 | EPHX1 (0.43) | CHRM3BCHEEPHX1MEN1KMT2A | |
| SCHEMBL9333191 | 0.81 | EPHX1 (0.43) | CHRM3BCHEEPHX1MEN1KMT2A | |
| SCHEMBL9019503 | 0.78 | TDP1 (0.40) | BCHEEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4889799 | 0.76 | GSR (0.39) | CHRM3MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL9333430 | 0.75 | CHRM3 (0.38) | CHRM3BCHEEPHX1MEN1KMT2A | |
| SCHEMBL9795326 | 0.74 | TDP1 (0.61) | BCHEEPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL9348981 | 0.73 | LMNA (0.43) | EPHX1KMT2AALDH1A1 | |
| SCHEMBL9330460 | 0.73 | GAA (0.40) | CHRM3BCHEEPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |