Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333285 | 1.00 | EPHX1 (0.39) | EPHX1DRD2CHRM3LMNAHTR1A | |
| SCHEMBL9348740 | 0.82 | DRD2 (0.40) | DRD2LMNAHTR2AMEN1KMT2A | |
| SCHEMBL9329950 | 0.82 | EPHX1 (0.43) | EPHX1DRD2CHRM3LMNAHTR1A | |
| SCHEMBL9333191 | 0.82 | EPHX1 (0.43) | EPHX1DRD2CHRM3LMNAHTR1A | |
| SCHEMBL7816311 | 0.76 | DRD2 (0.46) | EPHX1DRD2KMT2A | |
| SCHEMBL9333430 | 0.74 | CHRM3 (0.38) | EPHX1CHRM3HTR2ABCHEMEN1 | |
| SCHEMBL9330460 | 0.72 | GAA (0.40) | EPHX1CHRM3HTR2ABCHETMEM97 | |
| SCHEMBL9332557 | 0.72 | CHRM3 (0.37) | CHRM3LMNAHTR2AMEN1KMT2A | |
| SCHEMBL9329933 | 0.72 | UGT8 (0.36) | EPHX1CHRM3BCHEMEN1KMT2A | |
| SCHEMBL9333289 | 0.72 | UGT8 (0.36) | EPHX1CHRM3BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |