Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329505 | 0.75 | MAOB (0.48) | MAOBMAOA | |
| SCHEMBL6490749 | 0.73 | MAOB (0.72) | NPC1RAB9AMAOBGPR35KDM4E | |
| SCHEMBL31001114 | 0.72 | GAA (0.65) | NPC1RAB9AKDM4EMEN1GAA | |
| SCHEMBL29628919 | 0.72 | GPR35 (0.76) | L3MBTL1MAOBGPR35KDM4EMAOA | |
| SCHEMBL980268 | 0.72 | GPR35 (0.76) | L3MBTL1MAOBGPR35KDM4EMAOA | |
| SCHEMBL9329983 | 0.71 | POLB (0.53) | NPC1RAB9AMAOBGPR35KDM4E | |
| SCHEMBL15744786 | 0.71 | ALDH1A1 (0.74) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9331318 | 0.69 | ERCC1 (0.57) | L3MBTL1KDM4EMEN1GAAHTT | |
| SCHEMBL34468932 | 0.68 | NPC1 (1.00) | NPC1RAB9AL3MBTL1MAOBKDM4E | |
| SCHEMBL18993405 | 0.68 | MAOB (0.57) | NPC1RAB9AMAOBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |