Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329188 | 0.87 | TP53 (0.47) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL25060413 | 0.84 | ALDH1A1 (0.52) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL23027133 | 0.84 | ALDH1A1 (0.52) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL1642202 | 0.83 | ALDH1A1 (0.52) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL21220029 | 0.83 | ALDH1A1 (0.52) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL27686349 | 0.83 | ATM (0.46) | HPGD | |
| SCHEMBL6336853 | 0.83 | ATM (0.46) | HPGD | |
| SCHEMBL9330312 | 0.81 | TP53 (0.57) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8770287 | 0.80 | CTRB1 (0.49) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL9709725 | 0.80 | HPGD (0.48) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387605-B1 | Process for the stereoselective preparation of optically active S,S or R,R-beta-aminoalcohols | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0387605-A2 | Process for the stereoselective preparation of optically active S,S or R,R-beta-aminoalcohols | BAYER AG (DE) | 1990-09-19 | — | — | EP | disclosed |