Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 5/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330735 | 0.90 | KEAP1 (0.39) | CHRM3 | |
| Fumaric Acid SCHEMBL9348851 | 0.88 | CHRM3 (0.38) | ALOX15CHRM3PRMT3CARM1PRMT6 | |
| SCHEMBL9330677 | 0.82 | HRH3 (0.40) | CHRM3 | |
| SCHEMBL5154489 | 0.82 | SLC18A3 (0.38) | GSRCA2 | |
| SCHEMBL5153918 | 0.82 | GSR (0.33) | GSR | |
| Fumaric Acid SCHEMBL9345668 | 0.80 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL5148816 | 0.79 | GSR (0.35) | GSR | |
| SCHEMBL9330340 | 0.78 | SMN1; SMN2 (0.40) | CHRM3GSR | |
| SCHEMBL9330759 | 0.77 | GNAO1 (0.50) | CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL4585987 | 0.77 | ALDH1A1 (0.35) | CARM1PRMT6GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | claimed |
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |