Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.74 |
| ▸ | DRD2 | P14416 | 14/20 | 0.74 |
| ▸ | DRD3 | P35462 | 11/20 | 0.74 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429857 | 0.94 | DRD4 (0.70) | DRD4DRD2DRD3HTR1BKCNA3 | |
| SCHEMBL10476759 | 0.87 | DRD4 (0.95) | DRD4DRD2DRD3HTR1BKCNA3 | |
| SCHEMBL8773760 | 0.86 | LTA4H (0.65) | DRD4DRD2DRD3 | |
| SCHEMBL11896615 | 0.85 | DRD4 (1.00) | DRD4DRD2DRD3HTR1BKCNA3 | |
| Hydrochloric Acid SCHEMBL8054973 | 0.85 | DRD4 (0.91) | DRD4DRD2DRD3HTR1BKCNA3 | |
| Hydrochloric Acid SCHEMBL8055377 | 0.83 | DRD4 (0.96) | DRD4DRD2DRD3HTR1BKCNA3 | |
| SCHEMBL11895289 | 0.81 | DRD2 (0.83) | DRD4DRD2DRD3HTR1BKCNA3 | |
| SCHEMBL8938905 | 0.81 | DRD4 (0.91) | DRD4DRD2DRD3HTR1BKCNA3 | |
| SCHEMBL8773767 | 0.80 | LTA4H (0.59) | DRD4DRD2DRD3GAA | |
| SCHEMBL22144524 | 0.80 | DRD4 (0.74) | DRD4DRD2DRD3HTR1BKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | claimed |
| US-4999377-A | 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds; dietetics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | claimed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | claimed |
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-4999377-A | 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds; dietetics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | disclosed |