Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 13/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251895 | 0.91 | THRB (0.83) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6721049 | 0.85 | THRB (0.59) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6721055 | 0.85 | RAB9A (0.71) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9332548 | 0.83 | MAPT (0.57) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2245965 | 0.82 | MAPT (0.69) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2246322 | 0.81 | MAPT (0.67) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6721054 | 0.81 | MAPT (0.87) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2246778 | 0.80 | MAPT (0.66) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2244745 | 0.79 | MAPT (0.87) | THRBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6721053 | 0.77 | THRB (0.62) | THRBMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5277839-A | Guidepath material | LITTON INDUSTRIAL AUTOMATION AUTOMATED VEHICLES (US) | 1994-01-11 | — | — | US | disclosed |