SCHEMBL9330865

SCHEMBL9330865

CCn1c(C)cc(=O)c(C(=O)O)c1-c1cccc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 3/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 1/20 0.44
MDM2 Q00987 4/20 0.44
PGR P06401 1/20 0.43
APOBEC3G Q9HC16 1/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PIN1 Q13526 1/20 0.39
NOTUM Q6P988 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333871 0.90 MDM2 (0.42) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL10462909 0.88 ALDH1A1 (0.44) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL9330776 0.87 ALDH1A1 (0.57) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL9330583 0.86 ALDH1A1 (0.43) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL9331069 0.86 CNR2 (0.43) MDM2
SCHEMBL122379 0.86 KMT2A (0.49) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL9330825 0.85 KDM4E (0.44) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL10463549 0.85 KMT2A (0.48) RAB9AALDH1A1KDM4EPOLBHPGD
SCHEMBL9330760 0.84 POLB (0.43) ALDH1A1KDM4EPOLBHPGDHTT
SCHEMBL9333422 0.83 MDM2 (0.45) RAB9AKDM4EMDM2PGRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364183-B1 Chemical hybridisation of dicots ZENECA LTD (GB) 1994-03-30 EP disclosed
US-4964896-A GAMETOCIDES MONSANTO COMPANY (US) 1990-10-23 US disclosed
US-4936904-A Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants MONSANTO TECHNOLOGY LLC 1990-06-26 US disclosed
EP-0364183-A2 Chemical hybridisation of dicots ZENECA LIMITED (GB) 1990-04-18 EP disclosed
EP-0127313-B1 THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-07-19 EP disclosed
US-4714492-A HYBRIDIZATION AGENTS ROHM AND HAAS COMPANY (US) 1987-12-22 US disclosed
EP-0127313-A1 The production of haploid seed, of doubled haploids and of homozygous plant lines therefrom CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1984-12-05 EP disclosed
EP-0040082-B1 NOVEL SUBSTITUTED OXONICOTINATES, THEIR USE AS PLANT GROWTH REGULATORS AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM ROHM AND HAAS COMPANY (US) 1984-04-25 EP disclosed
EP-0040082-A1 Novel substituted oxonicotinates, their use as plant growth regulators and plant growth regulating compositions containing them ROHM AND HAAS COMPANY (US) 1981-11-18 EP disclosed