SCHEMBL933150

SCHEMBL933150

CCn1cc[n+](C)c1.COCCS(=O)(=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
PLA2G1B P04054 1/20 0.36
HSP90AA1 P07900 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3947403 0.87 SMN1; SMN2 (0.36) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL932213 0.86 MEN1 (0.52) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL28886950 0.84 SMN1; SMN2 (0.44) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL411942 0.84 SMN1; SMN2 (0.44) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL413686 0.83 NPSR1 (0.41) FDPSSMN1; SMN2MEN1APAF1NPC1
Sulfuric Acid SCHEMBL2325415 0.82 SMN1; SMN2 (0.46) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL2356655 0.82 SMN1; SMN2 (0.49) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL16968717 0.82 RECQL (0.41) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL295310 0.82 SMN1; SMN2 (0.37) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL295578 0.81 SMN1; SMN2 (0.44) FDPSSMN1; SMN2MEN1APAF1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772438-B2 Preparation of polyamides Invista North America S.är.l. (US) 2014-07-08 US claimed
US-20120264907-A1 PREPARATION OF POLYAMIDES INVISTA NORTH AMERICA S.A.R.L. (US) 2012-10-18 US claimed
EP-2451863-A1 PREPARATION OF POLYAMIDES Invista Technologies S.A R.L. (CH) 2012-05-16 EP claimed
WO-2011004138-A1 PREPARATION OF POLYAMIDES INVISTA TECHNOLOGIES S.A.R.L. (CH) 2011-01-13 WO claimed
EP-2051788-A1 EXTRACTION PROCESS USING AN IONIC LIQUID Invista Technologies S.à.r.l. (CH) 2009-04-29 EP claimed
US-7442841-B2 Extraction process INVISTA NORTH AMERICA S.A R.L. (US) 2008-10-28 US claimed
US-20080051609-A1 EXTRACTION PROCESS INVISTA NORTH AMERICA S.A.R.L. (US) 2008-02-28 US claimed
WO-2008022233-A1 EXTRACTION PROCESS USING AN IONIC LIQUID INVISTA TECHNOLOGIES S.A.R.L. (CH) 2008-02-21 WO claimed
US-8772438-B2 Preparation of polyamides Invista North America S.är.l. (US) 2014-07-08 US disclosed
US-20120264907-A1 PREPARATION OF POLYAMIDES INVISTA NORTH AMERICA S.A.R.L. (US) 2012-10-18 US disclosed
EP-2451863-A1 PREPARATION OF POLYAMIDES Invista Technologies S.A R.L. (CH) 2012-05-16 EP disclosed
WO-2011004138-A1 PREPARATION OF POLYAMIDES INVISTA TECHNOLOGIES S.A.R.L. (CH) 2011-01-13 WO disclosed
EP-2051788-A1 EXTRACTION PROCESS USING AN IONIC LIQUID Invista Technologies S.à.r.l. (CH) 2009-04-29 EP disclosed
US-7442841-B2 Extraction process INVISTA NORTH AMERICA S.A R.L. (US) 2008-10-28 US disclosed
US-20080051609-A1 EXTRACTION PROCESS INVISTA NORTH AMERICA S.A.R.L. (US) 2008-02-28 US disclosed
WO-2008022233-A1 EXTRACTION PROCESS USING AN IONIC LIQUID INVISTA TECHNOLOGIES S.A.R.L. (CH) 2008-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051609-A1 EXTRACTION PROCESS ADH1C, ADH1A, ADH5 FDPS 1591/4885SMN1; SMN2 3908/4885MEN1 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.