Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | FABP4 | P15090 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | F3 | P13726 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331814 | 1.00 | FFAR1 (0.54) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL28838071 | 0.91 | TERT (0.58) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL28787207 | 0.91 | TERT (0.58) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL28410211 | 0.91 | TERT (0.58) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL5370133 | 0.89 | PPARG (0.55) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL5370135 | 0.89 | PPARG (0.55) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL8331964 | 0.87 | F7 (0.58) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL7213085 | 0.87 | F7 (0.58) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL30830433 | 0.86 | ALDH1A1 (0.61) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL7941758 | 0.85 | FAAH (0.48) | FFAR1FFAR4PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364517-B1 | PREVENTION OF PROSTHESIS CALCIFICATION | BIOMEDICAL DESIGN INC (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0364517-A4 | PREVENTION OF PROSTHESIS CALCIFICATION | — | 1991-01-16 | — | — | EP | disclosed |
| US-4976733-A | USING ALIPHATIC CARBOXYLIC ACID | BIOMEDICAL DESIGN, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0364517-A1 | PREVENTION OF PROSTHESIS CALCIFICATION. | BIOMEDICAL DESIGN INC (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989006945-A1 | PREVENTION OF PROSTHESIS CALCIFICATION | BIOMEDICAL DESIGN, INC. (US) | 1989-08-10 | — | — | WO | disclosed |