Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 5/20 | 0.33 |
| ▸ | FNTB | P49356 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9331918 | 0.74 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRMAPT | |
| Fumaric Acid SCHEMBL9331904 | 0.74 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9784933 | 0.72 | BCHE (0.38) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9331357 | 0.71 | LMNA (0.41) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9758897 | 0.71 | LMNA (0.41) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9784853 | 0.71 | BCHE (0.37) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9759527 | 0.70 | PTGS1 (0.37) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9759522 | 0.70 | PTGS1 (0.37) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9759380 | 0.69 | BCHE (0.35) | BCHECYP2D6CYP2C19TSHRMAPT | |
| SCHEMBL9784916 | 0.69 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321026-A | Antispasmodic agents | RHONE-POULENC RORER S.A. (FR) | 1994-06-14 | — | — | US | disclosed |
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |