Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759522 | 1.00 | PTGS1 (0.37) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9759954 | 0.86 | PTGS1 (0.40) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9759957 | 0.79 | PTGS1 (0.40) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9759757 | 0.78 | LMNA (0.43) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9759761 | 0.78 | LMNA (0.43) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9331908 | 0.70 | BCHE (0.35) | CYP2D6HTR1ADRD3ALDH1A1CYP1A2 | |
| SCHEMBL9331357 | 0.68 | LMNA (0.41) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9758897 | 0.68 | LMNA (0.41) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9791007 | 0.67 | MAOA (0.48) | PTGS1PTGS2CYP2D6HTR1ADRD3 | |
| SCHEMBL9759932 | 0.66 | LMNA (0.40) | PTGS1PTGS2CYP2D6HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |