Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | CPT2 | P23786 | 5/20 | 0.32 |
| ▸ | CPT1A | P50416 | 5/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933195 | 1.00 | MAPT (0.32) | MAPTDGAT1CPT2CPT1ASCD | |
| SCHEMBL831054 | 0.88 | ALDH1A1 (0.41) | MAPTTP53 | |
| SCHEMBL205382 | 0.88 | ALDH1A1 (0.41) | MAPTTP53 | |
| SCHEMBL934406 | 0.88 | DGAT1 (0.32) | MAPTDGAT1CPT2CPT1ASCD | |
| SCHEMBL934404 | 0.88 | DGAT1 (0.32) | MAPTDGAT1CPT2CPT1ASCD | |
| SCHEMBL16499389 | 0.86 | F11 (0.32) | CPT2CPT1AF11 | |
| SCHEMBL749358 | 0.86 | DGAT1 (0.33) | DGAT1CPT2CPT1ASCDSCD5 | |
| SCHEMBL10118256 | 0.85 | PREP (0.45) | — | |
| SCHEMBL27978679 | 0.85 | TP53 (0.31) | MAPTDGAT1CPT2CPT1ASCD | |
| SCHEMBL18418054 | 0.84 | DGAT1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| WO-2011004276-A1 | HEPATITIS C VIRUS INHIBITORS | PFIZER LIMITED (GB) | 2011-01-13 | — | — | WO | disclosed |