Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 3/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261956 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL6403148 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| Iodide SCHEMBL29561357 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| Iodide SCHEMBL21814312 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL9332274 | 0.71 | AXL (0.36) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL29365003 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL48843 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL27912581 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL9332293 | 0.66 | ACHE (0.46) | — | |
| Hydrochloric Acid SCHEMBL8641121 | 0.66 | CYP3A4 (0.93) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315997-B1 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| US-4971961-A | ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |