Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979932 | 0.85 | OPRM1 (0.41) | OPRM1SPHK1SLC15A1TP53LAP3 | |
| SCHEMBL3263688 | 0.81 | ALDH1A1 (0.43) | OPRM1SPHK1SLC15A1TP53LAP3 | |
| SCHEMBL2099612 | 0.76 | OPRM1 (0.44) | OPRM1SPHK1SLC15A1TP53ALDH1A1 | |
| SCHEMBL8979964 | 0.76 | OPRM1 (0.44) | OPRM1SPHK1SLC15A1TP53LAP3 | |
| SCHEMBL9331989 | 0.76 | — | — | |
| SCHEMBL8979945 | 0.75 | OPRM1 (0.50) | OPRM1SPHK1TP53LAP3ALDH1A1 | |
| SCHEMBL635647 | 0.75 | DNM1 (0.41) | OPRM1ALDH1A1TDP1 | |
| SCHEMBL2053283 | 0.73 | OPRM1 (0.43) | OPRM1SPHK1SLC15A1TP53LAP3 | |
| SCHEMBL15299174 | 0.71 | DNM1 (0.38) | OPRM1ALDH1A1TDP1 | |
| SCHEMBL1484167 | 0.68 | OPRM1 (0.50) | OPRM1SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280499-B1 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0280499-A2 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-08-31 | — | — | EP | disclosed |
| US-4705877-A | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |