Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332821 | 1.00 | ADRB3 (0.70) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| Hydrochloric Acid SCHEMBL9332705 | 0.99 | ALOX15 (0.70) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| Hydrochloric Acid SCHEMBL9332693 | 0.99 | ALOX15 (0.70) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| SCHEMBL9332734 | 0.86 | KDM4E (0.71) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| SCHEMBL9333215 | 0.86 | KDM4E (0.71) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| SCHEMBL10720145 | 0.86 | ADRB2 (0.77) | ADRB3ADRB2KDM4EGAASMN1; SMN2 | |
| SCHEMBL12835897 | 0.85 | ADRB3 (0.70) | ADRB3ADRB1ADRB2KDM4EGAA | |
| Hydrochloric Acid SCHEMBL9333230 | 0.85 | KDM4E (0.70) | ADRB3ADRB1ALOX15ADRB2KDM4E | |
| SCHEMBL4467885 | 0.83 | ADRB2 (0.73) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL9543386 | 0.83 | ADRB2 (0.73) | ADRB3ADRB1ADRB2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591503-A1 | 4-[2-(2-HYDROXY-2-PHENYLETHYLAMINO)ETHYL]PHENYLACETIC ACID AS BETA 3-ADRENOCEPTOR-AGONIST | ZENECA LIMITED (GB) | 1994-04-13 | — | — | EP | claimed |
| WO-1993022277-A1 | 4-[2-(2-HYDROXY-2-PHENYLETHYLAMINO)ETHYL]PHENYLACETIC ACID AS BETA3-ADRENOCEPTOR-AGONIST | ZENECA LIMITED (GB) | 1993-11-11 | — | — | WO | claimed |
| EP-0591503-A1 | 4-[2-(2-HYDROXY-2-PHENYLETHYLAMINO)ETHYL]PHENYLACETIC ACID AS BETA 3-ADRENOCEPTOR-AGONIST | ZENECA LIMITED (GB) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993022277-A1 | 4-[2-(2-HYDROXY-2-PHENYLETHYLAMINO)ETHYL]PHENYLACETIC ACID AS BETA3-ADRENOCEPTOR-AGONIST | ZENECA LIMITED (GB) | 1993-11-11 | — | — | WO | disclosed |